Alexander the Great's vast empire shattered into pieces. From one of those pieces, something small and unexpected began to grow.
Daniel's vision shows a continuation of the previous imagery. The great ram with the notable horn (representing Alexander and his empire) was broken, and four horns (representing the four kingdoms that divided his empire) arose in its place.
Now, out of one of these four, a 'little horn' emerges. This isn't a completely new power, but one that originates within an existing division of Alexander's former empire. This detail is crucial: the prophecy isn't about an external force, but a development from within the Hellenistic world. Many scholars point to Antiochus Epiphanes, a king from the Seleucid (Syrian) dynasty, as the primary fulfillment of this 'little horn'. He was a younger son, not initially destined for the throne, and a hostage in Rome, fitting the description of 'little' at his rise.